Kelsey Grammer was briefly the highest paid television actor in the U.S. for his portrayal of Frasier, while Jane Leeves was the highest paid British actress.
Following his many appearances on Cheers, Grammer tied the record for the longest running character in prime time, equaling James Arness’ twenty years as Marshal Dillon on Gunsmoke.
Niles’ existence as Frasier’s brother creates a Cheers continuity flaw, since Frasier once mentioned that he was an only child.
Lisa Kudrow auditioned for the part of Roz Doyle.
Only one episode was filmed in Seattle—S5E5: “The 1000th Show” (which was the 101st episode).